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Identifying and Avoiding DNA sequences

HMM Imagine that you want to create a drug that attacks the DNA of one class of organisms, yet is harmless with respect to another organism's DNA. For example, if a human is infected with some bacterium, one might want to have a drug which is lethal for the bacterium and its close relatives but not so lethal for the host (legalities and ethics prevail). This work describes approximate algorithms for identifying DNA sequences which are approximately shared amongst a group of organisms, but absent from the DNA of another group.

Publications

  
 
Dynamic Graphics Project Department of Computer Science University of Toronto

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